Sindh MDCAT 2026 Past Paper

41- Information from the spinal cord is transmitted to an effector through a:

A. Receptor
B. Relay neuron
C. Sensory neuron
D. Motor neuron

Answer : D. Motor neuron

42- Which of the following is NOT a part of the brain?

A. Pituitary gland
B. Hypothalamus
C. Corpus callosum
D. Cerebellum

Answer : A. Pituitary gland

43- The right and left cerebral hemispheres are connected by the:

A. Hypothalamus
B. Cerebellum
C. Corpus callosum
D. Medulla oblongata

Answer : C. Corpus callosum

44- Which part of the brain is associated with emotional responses such as pleasure and fear?

A. Pons
B. Cerebellum
C. Amygdala
D. Medulla oblongata 

Answer : C. Amygdala

45- Which part of the brain plays a major role in controlling the autonomic nervous system?

A. Hypothalamus
B. Cerebellum
C. Medulla only
D. Corpus callosum

Answer : A. Hypothalamus

46- Which phase of the menstrual cycle is most directly associated with the LH surge?

A. Follicular phase
B. Menstrual phase
C. Luteal phase
D. Ovulatory phase

Answer : D. Ovulatory phase

47- Which of the following is NOT a sexually transmitted disease?

A. Gonorrhea
B. Syphilis
C. HIV/AIDS
D. Hemophilia

Answer : D. Hemophilia

48- Which of the following best defines a monoclonal antibody?

A. Antibodies that bind to a specific antigenic epitope
B. Antibodies that bind only to the host cell surface
C. Antibodies that bind only to the pathogen cell surface
D. Antibodies produced by different types of B-lymphocytes

Answer : A. Antibodies that bind to a specific antigenic epitope

49- Genetic diseases can be treated by gene therapy by:

A. Inserting a functional gene into the patient’s cells
B. Removing all genes from the patient’s cells
C. Increasing the number of chromosomes
D. Replacing all proteins in the patient’s body

Answer : A. Inserting a functional gene into the patient's cells

50- When two heterozygous organisms (AaBb) are crossed, the probability of obtaining an organism with genotype AABB is:

A. 1/4
B. 1/8
C. 1/16
D. 3/16

Answer : C. 1/16

51- The law which explains that the two alleles of a gene separate randomly during gamete formation is:

A. Law of Segregation
B. Law of Independent Assortment
C. Law of Dominance
D. Law of Linkage

Answer : A. Law of Segregation

52- During self-crossing of a heterozygous organism, the alleles of a gene:

A. Remain together in the same gamete
B. Produce heterozygous offspring only
C. Produce homozygous offspring only
D. Segregate randomly, producing a phenotypic ratio of 3:1

Answer : D. Segregate randomly, producing a phenotypic ratio of 3:1

53- A male suffers from an X-linked recessive disease and dies at the age of 3 years. A female has an allele identical to that present in the affected male but survives. The female is most likely:

A. An affected female
B. An affected male
C. A carrier female
D. A homozygous normal female

Answer : C. A carrier female

54- Which type of genetic disease is generally more common in females than in males?

A. X-linked recessive
B. X-linked dominant
C. Y-linked
D. Autosomal recessive

Answer : B. X-linked dominant

55- The concept of "use and disuse of organs" was proposed by:

A. Charles Darwin
B. Gregor Mendel
C. Alfred Russel Wallace
D. Jean-Baptiste Lamarck

Answer : D. Jean-Baptiste Lamarck

56- Eukaryotic cells are believed to have evolved from:

A. Viruses
B. Prokaryotic cells
C. Multicellular organisms
D. Viruses and bacteriophages

Answer : B. Prokaryotic cells

57- Enzymes increase the rate of a chemical reaction by:

A. Increasing the temperature
B. Increasing the activation energy
C. Increasing the concentration of products
D. Lowering the activation energy

Answer : D. Lowering the activation energy

58- Inflammation of body tissues is mainly associated with an increased level of:

A. Glucagon
B. Thyroxine
C. Insulin
D. Prostaglandins

Answer : D. Prostaglandins

59- Protein digestion in the stomach is reduced due to decreased activation of pepsinogen, which may occur because of a lack of:

A. Bile
B. HCl
C. Pancreatic juice
D. Sodium bicarbonate

Answer : B. HCl

60- A chromosome with its centromere located near one end is called:

A. Metacentric
B. Submetacentric
C. Acrocentric
D. Telocentric

Answer : C. Acrocentric

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