Sindh MDCAT 2025 Past Paper

41- The appendix is attached to which part of large intestine?

A. Rectum
B. Caecum
C. Colon
D. Ileum

Answer : B. Caecum

42- Which structural characteristic is most accurate for arteries?

A. Thin walls with valves 
B. Thick and muscular walls 
C. Highly permeable walls 
D. Large lumen lacking muscle

Answer : B. Thick and muscular walls

43- A food sample contains long chains of amino acids bounded together. This indicates the presence of:

A. Carbohydrates
B. Lipids
C. Proteins
D. Nucleic acids

Answer : C. Proteins

44- Monoclonal antibodies are useful in cancer diagnosis by:

A. Replacing damaged tissue 
B. Changing the genetic code of cancer cells 
C. Killing healthy cells to reduce tumor spread 
D. Detecting specific tumor markers in samples

Answer : D. Detecting specific tumor markers in samples

45- The main function of the pharynx in respiratory system:

A. Serves as passage for both food and air
B. Produces mucus
C. Filters air
D. Produces voice 

Answer : A. Serves as passage for both food and air

46- The main cause of acute kidney failure is:

A. Less sweating 
B. Hypothermia
C. Liver failure
D. Drinking of excess water

Answer : C. Liver failure

47- During diastole, the heart chambers:

A. Relax and fill with blood
B. Contract strongly 
C. Remain closed
D. Eject blood into arteries 

Answer : A. Relax and fill with blood

48- Kidneys perform their osmoregulatory role under the effect of Antidiuretic Hormone, which type of urine is produced in this situation?

A. Hypotonic urine with decreased volume 
B. Hypotonic urine with increased volume 
C. Hypertonic urine with decreased volume
D. Hypertonic urine with increased volume

Answer : C. Hypertonic urine with decreased volume

49- A person has swollen lymph nodes after throat infection. What does this indicate?

A. Failure of circulatory system
B. Extra glucose storage 
C. Active immune response
D. Blockage of digestive track

Answer : C. Active immune response

50- Which of the following is correct about the structure of brain?

A. Cerebral cortex is outer part consists of grey matter
B. Cerebral medulla is inner part consists of grey matter 
C. Cerebral cortex is inner part consists of white matter 
D. Cerebral medulla is outer part consists of white matter

Answer : A. Cerebral cortex is outer part consists of grey matter

51- Under a microscope plant cells appeared rigid in shape, unlike flexible animal cells. Which structure explain this difference?

A. Cell wall
B. Vacuole
C. Cytoskeleton
D. Plasma membrane

Answer : A. Cell wall

52- Which type of joint allows bending of the elbow joint and has a synovial cavity?

A. Cartilaginous joint 
B. Fibrous joint 
C. Pubic symphysis 
D. Hinge joint

Answer : D. Hinge joint

53- If a round seeded pea plant is self-fertilized and all of its offspring are also round seeded:

A. Both parents and offspring must be true breed 
B. Both parents and offspring may be true breed 
C. Only parents but not offspring will be true breed 
D. Only offspring but not parents will be true breed

Answer : A. Both parents and offspring must be true breed

54- A student observes a microorganism under a microscope that lacks a nucleus and is made of a single cell. Which classification would best fit this organism?

A. Unicellular prokaryote
B. Unicellular eukaryote 
C. Multicellular eukaryote 
D. Multicellular prokaryote

Answer : A. Unicellular prokaryote

55- In biotechnology vaccines can be developed by cloning of:

A. Gene for antigen of pathogen
B. Gene for receptor of the patient 
C. Gene for antigen of patient 
D. Gene for antibody of patient

Answer : A. Gene for antigen of pathogen

56- Atrioventricular valve closed during which phase of cardiac cycle:

A. Ventricular systole
B. Ventricular diastole 
C. Atrial systole 
D. Atrial diastole

Answer : A. Ventricular systole

57- If "RRYY" is crossed with "rryy", what will be the ratio of "RRYY" to "rryy" in F2 generation?

A. 9 : 3 : 3 : 1 
B. 3 : 1
C. 1 : 3
D. 1 : 1

Answer : D. 1 : 1

58- Name the idea of Darwin that best explains the ability of populations to reproduce those individuals who possess beneficial traits.

A. Gene flow 
B. Genetic drift 
C. Artificial selection 
D. Natural selection

Answer : D. Natural selection

59- At least how many saccharide units must be present in polysaccharide?

A. 1
B. 2
C. 10
D. 11

Answer : D. 11

60- A doctor taps below the knee and the leg kicks forward What does this show?

A. A conditional response 
B. Voluntary muscle contractions 
C. An involuntary reflex to external stimuli
D. A delayed response due to brain processing

Answer : C. An involuntary reflex to external stimuli

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